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Updated: Aug 26, 2025

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
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Chromosome-Level Genome Assembly of Trichoderma cornu-damae Using Hi-C Data

Sung-Eun Cho1, Young-Nam Kwag1, Dong-Hyeon Lee2

  • 1Forest Biodiversity Division, Korea National Arboretum, Pocheon, South Korea.

Microbiology Resource Announcements
|October 5, 2022
PubMed
Summary

Trichoderma cornu-damae, a poisonous mushroom, produces toxic trichothecene mycotoxins. Researchers created a chromosome-level genome assembly for this fungus using Hi-C sequencing technology.

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The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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