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Updated: Aug 26, 2025

Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses
Published on: June 14, 2020
[Varicella-Zoster Virus Infection in the Central Nervous System]
1JCHO Tokuyama Central Hospital.
Abstract:
Varicella-zoster virus (VZV) is known to causes various inflammatory disorders of the central nervous system (CNS) such as encephalitis, meningitis, and myelitis. Similar to the varicella rashes, these conditions are associated with the reactivation of VZV. Ganglionitis and vasculitis, in particular, may be linked to the pathogenesis of VZV infection in the CNS. This review provides an overview of the clinical presentation, diagnosis, treatment, and prognosis of VZV infection in the CNS based on its distinct pathophysiology.
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