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Isolation and structure of an epidermal mitosis inhibiting pentapeptide
Biochemical and Biophysical Research Communications
|August 14, 1987
Abstract:
A mitosis inhibiting peptide pyroGlu-Glu-Asp-Ser-GlyOH has been isolated from mouse skin extracts. Both the biological and a synthetic peptide with the same structure reversibly inhibit epidermal mitoses in a curvilinear fashion after intraperitoneal injection. The two compounds are chromatographically identical.