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High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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Hydrophobic Tag Tethering Degradation, The Emerging Targeted Protein Degradation Strategy

Jieke Gao1,2, Jiantao Zhang1,2, Xiaoli Han1,2

  • 1Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P.R. China.

Current Medicinal Chemistry
|October 6, 2022
PubMed

Keywords:
HyTTDsTargeted protein degradationdrug discoveryhydrophobic taghydrophobic tag tethering degraderstructure-activity relationship

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