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Published on: February 16, 2016
Metformin Can Be Safely Used in Patients Exposed to Contrast Media: A Systematic Review and Meta-Analysis
1Department of Cardiology, JinTan First People's Hospital, Changzhou, China.
Metformin use in patients undergoing contrast media procedures does not significantly increase the risk of contrast-induced acute kidney injury (CI-AKI). This systematic review found no evidence of increased CI-AKI or lactic acidosis in metformin-treated individuals.
Area of Science:
- Nephrology
- Pharmacology
- Radiology
Background:
- Limited research exists on contrast media (CM) use in metformin-treated patients.
- Contrast-induced acute kidney injury (CI-AKI) is a concern in patients receiving CM.
- Metformin is a common medication for type 2 diabetes.
Conclusions:
- Metformin can be safely administered to patients with moderate renal impairment (eGFR ≥ 30 mL/min/1.73 m2) during CM exposure.
- The study supports the continued use of metformin in patients undergoing procedures requiring CM.
- Further research may explore specific patient subgroups.
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