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Effects of pH and hypoglycemia on bilirubin cytotoxicity in vitro
Biology of the Neonate
|January 1, 1987
Abstract:
In this study the effects of pH and hypoglycemia on bilirubin cytotoxicity in vitro were examined by means of a 51Cr release assay. The bilirubin cytotoxicity, which was dose dependent, was increased at lower pH values. Cells, pre-exposed to the hypoglycemic state, became more resistant on incubation in culture medium containing glucose for 1 h in comparison with those exposed to the hypoglycemic state only.