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RanBP1 plays an essential role in directed migration of neural crest cells during development

Elias H Barriga1, Delan N Alasaadi2, Chiara Mencarelli3

  • 1Cell and Developmental Biology, University College London, London, WC1E 6BT, United Kingdom; Mechanisms of Morphogenesis Lab, Instituto Gulbenkian de Ciencia, Oeiras, 2780-156, Portugal.

Developmental Biology
|October 7, 2022
PubMed
Summary

Ran-binding protein 1 (RanBP1) is crucial for directed collective cell migration, enabling neural crest cells to move towards external cues. This protein establishes cell polarity, essential for processes like embryonic development and cancer metastasis.

Keywords:
Cell migrationLKB1Neural crest cellsNucleocytoplasmic transportRanBP1

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