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Published on: September 12, 2014
Applications of acellular human amniotic membrane in regenerative medicine
Shaghayegh Doudi1, Mansoureh Barzegar2, Elham Angouraj Taghavi1
1Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran.
Abstract:
The human amniotic membrane (hAM) surrounds and protects the fetus. It mainly consists of a thick basement membrane and an avascular stromal matrix. The structural, physical, and biological properties of AM make it a wonderful choice to use in regenerative medicine applications. This review discusses recent applications of hAM in skin transplantation and wound healing, ophthalmology, orthopedics, cell culture matrix, cell delivery system, cardiac injury, male and female reproductive systems, and liver. Moreover, an overview is presented on the advantages and disadvantages of using hAM and some methods to systematically refine and standardize hAM preparation.

