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Updated: Aug 26, 2025

Author Spotlight: Investigating the Key Factors of Obliterative Bronchiolitis After Lung Transplantation
Published on: November 10, 2023
Acute Dyspnea After Lung Transplantation: A Twisted Tale
Subha Ghosh1, Harpreet Singh Grewal2, Douglas Johnston3
1Cleveland Clinic Foundation, Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH.
Case Presentation:
A 67-year-old woman developed sudden-onset severe dyspnea 24 h after a bilateral sequential lung transplant for COPD. She had an uneventful surgery performed on cardiopulmonary bypass support. She required two units of packed RBCs as well as fresh frozen plasma during the surgery. She was successfully extubated within 12 h of surgery. Her primary graft dysfunction score was grade 2, 1, and 1 at 0, 12, and 24 h, respectively. Approximately 24 h after the procedure, she complained of increasing shortness of breath without fever, chills, cough, or pleuritic chest pain.
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