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Sleep Disturbances in Neurological Disease: A Target for Intervention
Seva G Khambadkone1, Sara E Benjamin2,3
1Department of Pediatrics, Oregon Health & Science University, Portland, Oregon.
Seminars in Neurology
|October 10, 2022
Summary
Disturbed sleep is common and impacts neurological health. Addressing sleep issues may modify the course of neurological diseases like epilepsy, stroke, and Parkinson's.
Area of Science:
- Neurology
- Sleep Medicine
- Public Health
Background:
- Sleep is vital for neurological health, yet sleep disturbances are prevalent and often overlooked.
- Neurological disorders such as epilepsy, headache, ischemic stroke, Parkinson's disease, and Alzheimer's disease significantly impact global health.
- The interplay between sleep disturbances and neurological disease risk/severity requires further investigation.
Approach:
- Overview of sleep biology, requirements, and common disorders.
- Review of evidence linking sleep disturbances to five major neurological diseases.
- Synthesis of clinical guidelines and literature for managing sleep issues in neurological patients.
Key Points:
- Sleep disturbances are linked to increased risk and severity in epilepsy, headache, stroke, Parkinson's, and Alzheimer's disease.
- Interventions targeting sleep problems may offer disease-modifying benefits for these neurological conditions.
- Clinical guidelines and literature support the evaluation and management of sleep disturbances in neurological care.
Conclusions:
- Integrating sleep assessment and management into neurological practice is crucial.
- Future research should focus on the bidirectional relationship between sleep and neurological health.
- Physicians should consider sleep-related recommendations for patients with or at risk of neurological disease.
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