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Independent risk factors affecting hemorrhage in percutaneous nephrolithotomy: Retrospective study
1Health Sciences University, Gaziosmanpaşa Education and Research Hospital, Urology Clinic, Estambul, Turkey.
Actas Urologicas Espanolas
|October 10, 2022
Summary
Bleeding after percutaneous nephrolithotomy (PNL) is a concern. Neutrophil count, mean platelet volume, neutrophil-lymphocyte ratio, and platelet count are key predictors of blood loss during PNL.
Area of Science:
- Urology
- Nephrology
- Surgical Complications
Background:
- Bleeding is a primary concern during and after percutaneous nephrolithotomy (PNL).
- Identifying risk factors for hemorrhage is crucial for patient safety and procedural outcomes.
Purpose of the Study:
- To determine independent risk factors associated with blood loss during PNL.
- To evaluate the impact of various patient and stone characteristics on perioperative hemorrhage.
Main Methods:
- A study included 308 adult patients undergoing PNL.
- Non-contrast computed tomography (NCCT) assessed renal anatomy, stone size, and Hounsfield units (HU).
- Hemoglobin (Hgb) variation was analyzed against numerous clinical, laboratory, and stone parameters.
Main Results:
- Mean Hgb variation was 2.1 (SD: 1.6).
- Significant correlations were found between Hgb variation and neutrophil count (NEU), mean platelet volume (MPV), neutrophil-lymphocyte ratio (NLR), stone volume, and HU.
- Platelet count (PLT) showed a significant negative correlation with Hgb variation.
Conclusions:
- NEU count, MPV, NLR, and PLT count are potential independent risk factors for predicting blood loss in PNL.
- Stone volume and HU also correlate with hemorrhage, alongside specific hematological parameters.
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