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Asymptomatic toxocariasis in children. A prospective study and treatment trial
Insights
A study found 16% of Hispanic children had Toxocara canis infections, often shared with family. Asymptomatic cases showed no immediate issues, but long-term risks like ocular disease remain possible.
Area of Science:
- Veterinary Medicine
- Parasitology
- Pediatrics
Background:
- Toxocara canis is a common roundworm parasite.
- Infection in children can lead to visceral larva migrans.
- Screening in primary care settings can identify at-risk populations.
Observation:
- A hospital-based clinic screened 153 Hispanic children.
- 16% prevalence of Toxocara canis infection was detected.
- Infections were present in household members of half the infected children.
Findings:
- Follow-up of asymptomatic cases for up to 7 years showed no clinical sequelae.
- The possibility of latent ocular disease requires longer-term observation.
- Thiabendazole treatment did not alter infection course in a 1-year controlled study.
Implications:
- Early detection of Toxocara canis infection is crucial.
- Further research is needed on long-term health outcomes.
- Current treatment protocols may require re-evaluation.
Abstract:
Screening of 153 Hispanic children attending a Hospital-based primary care clinic revealed a 16 percent prevalence of Toxocara canis infection. Infections were found in other household occupants for half of these children. Follow-up of 20 children (for periods of up to 7 years) with asymptomatic T. canis infection failed to demonstrate any clinical sequelae. However, longer periods would be necessary to entirely discount the possibility of latent ocular disease. Treatment with thiabendazole did not appear to alter the course of the infection in a controlled 1-year evaluation as measured by eosinophil counts and specific T. canis antibody titers.