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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Mitral valve stenosis in the current era: a changing landscape
Cristina Giannini1, Matteo Mazzola1, Nicola Riccardo Pugliese2
1Cardiac, Thoracic and Vascular Department, Azienda Ospedaliero-Universitaria Pisana.
Degenerative mitral stenosis (DMS) from mitral annulus calcification is rising in developed nations. New diagnostic and catheter-based treatments offer hope for reducing DMS-related illness and death.
Area of Science:
- Cardiology
- Valvular Heart Disease
- Medical Research
Background:
- Mitral stenosis causes transmitral flow obstruction due to mitral valve abnormalities.
- Rheumatic fever is the primary global cause, but degenerative mitral stenosis (DMS) from mitral annulus calcification (MAC) is increasing in developed countries.
- DMS and rheumatic mitral stenosis (RMS) differ significantly in pathophysiology, prognosis, and progression.
Purpose of the Study:
- To review current knowledge on the pathophysiology, diagnosis, and treatment of DMS and RMS.
- To highlight existing diagnostic and therapeutic strategies for degenerative mitral stenosis.
- To identify persisting uncertainties and future perspectives in managing DMS.
Main Methods:
- Review of current literature on mitral stenosis, focusing on degenerative and rheumatic causes.
- Analysis of differences in pathophysiology, prognosis, and disease progression between DMS and RMS.
- Evaluation of emerging diagnostic techniques and catheter-based interventions for DMS.
Main Results:
- Degenerative mitral stenosis (DMS) due to mitral annulus calcification (MAC) is a growing concern in aging populations.
- Limited robust evidence currently exists for the management of DMS.
- Advancements in diagnostics and catheter-based interventions are emerging as promising avenues.
Conclusions:
- DMS presents distinct challenges compared to RMS, necessitating tailored management strategies.
- New diagnostic tools and interventional therapies are poised to improve outcomes for DMS patients.
- Further research is crucial to address current uncertainties and optimize the treatment of degenerative mitral stenosis.
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