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Updated: Aug 26, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Management of Psoriasis With Topicals: Applying the 2020 AAD-NPF Guidelines of Care to Clinical Practice
Vipawee S Chat1, Donovan G Kearns1, Shelley K Uppal1
1Dr. Chat is from the Medical College of Georgia, Augusta University. Dr. Kearns is from Loma Linda University School of Medicine, California. Dr. Uppal is from Albany Medical College, New York. Dr. Han is from the Department of Dermatology, Zucker School of Medicine at Hofstra/Northwell. Dr. Wu is from the Department of Dermatology, University of Miami Miller School of Medicine, Florida.
Abstract:
Topical medications have high utility in the treatment of psoriasis because of their localized effect and ability to be used as both monotherapy and adjunctive therapy. The American Academy of Dermatology (AAD) and the National Psoriasis Foundation (NPF) published guidelines in 2020 regarding the management of psoriasis with topical therapies. These guidelines are a framework that assist clinicians treating psoriasis patients with topical agents including steroids, calcineurin inhibitors (CNIs), vitamin D analogues, retinoids (tazarotene), emollients, keratolytics (salicylic acid), anthracenes (anthralin), and keratoplastics (coal tar). This review presents these evidence-based recommendations in a form that dermatologists can readily apply to their clinical practice. The selection of an appropriate topical therapy, effective combination therapies, duration of use, and adverse events are addressed.
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