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[Advances on optic disc morphological features and peripapillary structure changes in high myopia].
1Department of Ophthalmology, Hunan Children's Hospital, Changsha 410007, China.
[Zhonghua Yan Ke Za Zhi] Chinese Journal of Ophthalmology
|October 11, 2022
Summary
High myopia, a leading cause of vision loss, involves axial length elongation and posterior pole degeneration. This review examines optic disc and peripapillary changes to understand high myopia pathogenesis.
Area of Science:
- Ophthalmology
- Medical Research
Background:
- High myopia is a significant global cause of low vision and blindness.
- It is characterized by axial length elongation and degenerative changes in the fundus posterior pole.
Purpose of the Study:
- To review optic disc morphological features in high myopia.
- To examine peripapillary structure changes associated with high myopia.
- To elucidate the pathogenesis of high myopia and inform prevention/treatment strategies.
Main Methods:
- Literature review of studies on high myopia.
- Analysis of optic disc morphology.
- Assessment of peripapillary structure alterations.
Main Results:
- High myopia presents with optic disc tilt, altered optic cup and rim.
- Degenerative changes include chorioretinal atrophy, posterior staphyloma, and intrachoroidal cavitation.
- These changes are linked to prolonged axial length.
Conclusions:
- Optic disc and peripapillary changes are key features of high myopia.
- Understanding these morphological alterations is crucial for advancing prevention and treatment.
- Further research into pathogenesis may yield novel therapeutic approaches.

