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Updated: Aug 26, 2025
Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Electrochemically induced Markovnikov-type selective hydro/deuterophosphonylation of electron-rich alkenes
Weijie Deng1, Yunfei Hu1, Jinhui Hu1
1School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, 529090, P. R. China. wyuchemhyb@126.com.
Abstract:
The regioselective hydro/deuterophosphonylation of electron-rich alkenes with P(O)H compounds has been realized via a metal-free electrochemically induced strategy, accessing various Markovnikov-type adducts in high yields. A series of monodeuterated organophosphorus compounds with high deuterium (D) incorporation are subsequently obtained by adding D2O as the D source. The protocol features broad substrate scope, low energy consumption, high atom economy, and scalability. Monodeuterated organophosphoric acids can be synthesized via late-stage transformation.
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