[Modulation of the functional state of the brain using focused ultrasound]

The effects of focused ultrasonic action (SUA) on the brain functional state was found to depend on the intensity: there was no effect at 0.1 mWt/cm2 whereas an activation of the brain activity occurred at 1-100 mWt/cm2. The SUA 1-100 Wt/cm2 suppressed the ECoG. The mechanism of the SUA effect is supposed to be based on a change in permeability of neuronal membrane leading through a chain of intracellular molecular reactions to general de- or hyperpolarization of membranes of the neuronal populations and to a change in the brain activity.