[Relationship between valve ablation and bladder function in children with posterior urethral valves disorder]

Area of Science:

• Pediatric Urology
• Nephrology
• Surgical Innovation

Background:

• Posterior urethral valves (PUV) are a common cause of bladder outlet obstruction in male infants.
• PUV can lead to significant upper and lower urinary tract dysfunction.
• Early diagnosis and intervention are crucial for managing PUV complications.

Purpose of the Study:

• To evaluate the impact of valve ablation on bladder function in patients diagnosed with posterior urethral valves.
• To assess changes in urodynamic parameters and ultrasound findings post-ablation.
• To correlate surgical outcomes with upper urinary tract status.

Main Methods:

• Retrospective analysis of clinical data from patients with PUV.
• Urodynamic examinations performed before and after valve ablation.
• Postoperative urinary system ultrasound to assess residual urine volume and upper tract hydrocephalus.

Main Results:

• Valve ablation demonstrated limited overall improvement in bladder function.
• Significant improvements were observed in maximum bladder volume, residual urine volume, and maximum urine flow rate post-ablation.
• Patients with improved upper urinary tract hydrocephalus showed better outcomes in residual urine, bladder compliance, and maximum urine flow rate (P<0.05).

Conclusions:

• Valve ablation has a restricted effect on improving overall bladder function in PUV patients.
• Valve incision is beneficial for enhancing maximum bladder volume, reducing residual urine, and increasing maximum urine flow rate.
• The procedure shows a positive influence on bladder compliance and maximum detrusor pressure, particularly in cases with improved upper tract conditions.