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Could Endogenous Glucocorticoids Influence SARS-CoV-2 Infectivity?

Eugenio Hardy1, Carlos Fernandez-Patron2

  • 1Center of Molecular Immunology, P.O. Box 16040, Havana 11600, Cuba.

Cells
|October 14, 2022
PubMed
Summary

Glucocorticoids may directly combat SARS-CoV-2 by binding to the Spike protein, inhibiting viral entry into host cells. This interaction could offer a new strategy for developing antivirals against coronaviruses.

Keywords:
ACE2 (angiotensin converting enzyme 2)COVID-19SARS-CoV-2cortisoldexamethasoneglucocorticoidsinnate immunityspike protein

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