The Impact of COVID-19 on Lombardy Region ST-Elevation Myocardial Infarction Emergency Medical System Network-A
Giuseppe Stirparo1,2, Lorenzo Bellini1, Giuseppe Ristagno3,4
1Faculty of Medicine, School of Public Health, University of Vita-Salute San Raffaele, Via Olgettina 60, 20090 Milano, Italy.
Insights
The COVID-19 pandemic increased emergency medical system response times for ST-elevation myocardial infarction (STEMI) patients. However, pre-hospital treatment protocols, like fibrinolysis, remained unchanged during this period.
Area of Science:
- Cardiology
- Emergency Medicine
- Public Health
Background:
- The COVID-19 pandemic significantly disrupted emergency medical systems globally.
- Limited data exists on the pandemic's impact on ST-elevation myocardial infarction (STEMI) time-sensitive networks.
- Understanding these impacts is crucial for optimizing pre-hospital STEMI management, including fibrinolysis protocols.
Purpose of the Study:
- To investigate the effects of the COVID-19 pandemic on emergency medical system response times for STEMI patients.
- To assess changes in STEMI diagnosis rates and hospital access during the pandemic.
- To evaluate the adherence to pre-hospital clinical protocols during the pandemic.
Main Methods:
- Retrospective observational cohort study.
- Analysis of STEMI rescues from the Lombardy EMS registry (January 2019 - December 2021).
- Comparison of pre-pandemic, first wave, and later pandemic periods.
Main Results:
- A reduction in STEMI diagnoses was observed in March 2020 compared to March 2019 (OR 0.76).
- Average emergency medical mission times increased from 57.7 min in 2019 to 64.7 min in 2020 and 63.1 min in 2021.
- The number of specialized STEMI treatment centers (HUBs) decreased significantly from 52 pre-pandemic to 13 during the first wave.
Conclusions:
- The COVID-19 pandemic led to increased transportation times for STEMI patients.
- Despite longer transport times, the out-of-hospital clinical management approach for STEMI did not change.
- Fibrinolysis was not implemented in the out-of-hospital setting during the study period, irrespective of pandemic-related changes.
Abstract:
Objectives: The COVID-19 pandemic had a significant impact on emergency medical systems (EMS). Regarding the ST-elevation myocardial infarction (STEMI) dependent time network, however, there is little evidence linked to the post-pandemic phase regarding this issue. Such information could prove to be of pivotal importance regarding STEMI clinical management, especially pre-hospital clinical protocols such as fibrinolysis. Methods: A retrospective observational cohort study of all STEMI rescues recorded in the Lombardy EMS registry from the 1st of January 2019 to the 30th of December 2021. Results: Regarding the number of STEMI diagnoses, March 2020 (first pandemic wave in Italy) saw a reduction compared to March 2019 (OR 0.76 [0.60-0.93], p = 0.011). The average time of the entire mission increased to 63.1 min in 2021, reaching 64.7 min in 2020, compared with 57.7 min in 2019. The number of HUBs for STEMI patients saw a reduction, falling from 52 HUBs in the pre-pandemic phase to 13 HUBs during the first wave. Conclusions: During the pandemic phase, there was an increase in the transportation times of STEMI patients from home to the hospital. Such changes did not alter the clinical approach in the out-of-hospital phase. Indeed, the implementation of fibrinolysis was not required.
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