Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

7.1K
Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...
7.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishing a standard workflow for fluorescence-based nanoparticle tracking analysis for the reliable quantification of extracellular vesicles.

Methods (San Diego, Calif.)·2026
Same author

Review on Predictive Models and Integration Strategies for Holistic Impact Assessment of Chemicals and Materials.

Environmental science & technology·2026
Same author

CHIASMA: Advancing chemicals and materials safety and sustainability assessments through innovative integration of in vitro and in silico (new approach) methodologies.

Computational and structural biotechnology journal·2025
Same author

Discovering Heterogeneous Leukocytes Subsets Associated With Alcoholic Steatohepatitis by scRNAseq Analysis.

MedComm·2025
Same author

sEV-ICP-TOF-MS for Multiparametric Single-EV Analysis via Nanoparticle-Conjugated Antibodies and Isotope Ratio Filtering.

Analytical chemistry·2025
Same author

Immune Landscape Changes in MASLD and the Effects of 11β-HSD1 Inhibition Revealed by Single-Cell Mass Cytometry.

Proteomics. Clinical applications·2025

Related Experiment Video

Updated: Aug 25, 2025

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
13:51

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

15.5K

Upconversion Nanomaterials in Bioimaging and Biosensor Applications and Their Biological Response.

Zayakhuu Gerelkhuu1,2, Yong-Ill Lee3,4, Tae Hyun Yoon1,2,5

  • 1Department of Chemistry, College of Natural Sciences, Hanyang University, Seoul 04763, Korea.

Nanomaterials (Basel, Switzerland)
|October 14, 2022
PubMed
Summary
This summary is machine-generated.

Upconversion nanomaterials (UCNMs) offer unique optical properties for biomedical applications like drug delivery and bioimaging. This review covers their mechanisms, synthesis, applications, and biological responses, addressing clinical prospects and challenges.

Keywords:
bioimagingbiological responsebiosensorlanthanide-based nanomaterialsupconversion nanomaterials

More Related Videos

Harmonic Nanoparticles for Regenerative Research
09:23

Harmonic Nanoparticles for Regenerative Research

Published on: May 1, 2014

11.8K
An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
11:20

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation

Published on: August 30, 2017

7.5K

Related Experiment Videos

Last Updated: Aug 25, 2025

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
13:51

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

15.5K
Harmonic Nanoparticles for Regenerative Research
09:23

Harmonic Nanoparticles for Regenerative Research

Published on: May 1, 2014

11.8K
An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation
11:20

An Integrated System to Remotely Trigger Intracellular Signal Transduction by Upconversion Nanoparticle-mediated Kinase Photoactivation

Published on: August 30, 2017

7.5K

Area of Science:

  • Nanomaterials Science
  • Biomedical Engineering
  • Optical Physics

Background:

  • Upconversion nanomaterials (UCNMs) possess unique optical properties, including large anti-Stokes shifts and non-photobleaching.
  • These characteristics make UCNMs highly suitable for diverse biomedical applications.

Purpose of the Study:

  • To review the mechanisms, synthesis, and biological applications of UCNMs.
  • To discuss the biological responses and toxicity associated with UCNMs.
  • To explore the clinical prospects and future challenges of UCNMs in medicine.

Main Methods:

  • Literature review of upconversion mechanisms and synthesis techniques.
  • Analysis of UCNM applications in drug delivery, bioimaging, biosensing, and photodynamic therapy.
  • Evaluation of biological responses, toxicity, and intracellular mechanisms of UCNMs.

Main Results:

  • UCNMs exhibit promising potential for integrated biomedical applications.
  • Understanding UCNM biological responses and toxicity is crucial for clinical translation.
  • Significant opportunities exist for UCNMs in both biological research and clinical settings.

Conclusions:

  • UCNMs are versatile tools with significant potential in various biomedical fields.
  • Further research into UCNM safety and efficacy is needed for clinical adoption.
  • The future of UCNMs in medicine holds promise, contingent on overcoming current challenges.