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Updated: Aug 25, 2025

Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
[Perineal Metastatic Clear Cell Renal Cell Carcinoma: A Case Report]
Metastatic clear cell renal cell carcinoma (RCC) rarely involves the perineum. This case highlights the radiological changes of perineal metastatic RCC before and after targeted therapy.
Area of Science:
- Oncology
- Radiology
- Urology
Background:
- Metastatic renal cell carcinoma (RCC) can present with rare extra-renal manifestations.
- Perineal involvement by metastatic RCC is exceptionally uncommon, with limited documented radiological findings.
Observation:
- A 76-year-old female patient presented with perineal pain.
- The pain was attributed to metastatic clear cell RCC involving the perineal region.
Findings:
- The study details the radiological characteristics of a perineal metastatic clear cell RCC.
- It illustrates the tumor's changes observed on imaging, both prior to and following the initiation of targeted therapy.
Implications:
- This case contributes to the understanding of rare metastatic patterns in renal cell carcinoma.
- It underscores the importance of considering unusual presentations in the differential diagnosis of perineal pain.
- Radiological monitoring is crucial for assessing treatment response in metastatic RCC.
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