Jove
Visualize
Contact Us

Related Concept Videos

Sensitivity, Specificity, and Predicted Value01:13

Sensitivity, Specificity, and Predicted Value

611
In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
611

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Assessment of Stress Distribution in Three-dimensional-printed Implant Models Using Finite Element Analysis.

Annals of African medicine·2026
Same author

Diabetic Ketoacidosis in a Patient With Type 2 Diabetes Following Ophthalmic Steroid Use: A Rare Etiology.

Cureus·2026
Same author

The Role of TARE for Bridging and Downstaging of HCC Before Resection or Liver Transplant.

Cancers·2026
Same author

Prognostic factors for survival and recurrence in papillary thyroid carcinoma: a retrospective study.

Gland surgery·2025
Same author

The Impact of Additive and Subtractive Manufacturing on the Adhesion and Durability of Titanium-Zirconia Restorative Materials.

Journal of functional biomaterials·2025
Same author

Effect of uniaxial bending methods on the flexural strength and Weibull analysis of heat-polymerized, CAD/CAM milled, and 3D-printed denture base resins.

Dental materials : official publication of the Academy of Dental Materials·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Aug 25, 2025

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

19.9K

Factors Predicting Positive Sentinel Lymph Node Biopsy in Clinically Node-Negative Breast Cancer.

Thuraya S Alsumai1, Norah Alhazzaa1, Abdullah Alshamrani2

  • 1Department of Surgery, Section of Breast & Endocrine Surgery, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

Breast Cancer (Dove Medical Press)
|October 14, 2022
PubMed
Summary

Predictors of positive sentinel lymph node biopsy (SLNB) in early-stage breast cancer were identified. Tumor size, grade, receptor status, and lymphovascular invasion significantly predicted SLNB positivity in node-negative patients.

Keywords:
axillary lymph node dissectionaxillary metastasishormonal receptorslymphatic metastasis

More Related Videos

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

11.7K
Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

180

Related Experiment Videos

Last Updated: Aug 25, 2025

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy
07:51

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

19.9K
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

11.7K
Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model
07:13

Comparison of Predictive Performance of Three Lymph Node Staging Systems in Colorectal Signet Ring Cell Carcinoma Based on Machine Learning Model

Published on: April 18, 2025

180

Area of Science:

  • Oncology
  • Surgical Pathology
  • Breast Cancer Research

Background:

  • Sentinel lymph node biopsy (SLNB) is standard for staging the axilla in breast cancer.
  • Accurate prediction of positive SLNB in clinically node-negative patients is crucial for treatment planning.

Purpose of the Study:

  • To identify predictors of positive sentinel lymph node biopsy (SLNB) in breast cancer patients with clinically node-negative axilla.
  • To improve staging accuracy and guide treatment decisions for early-stage breast cancer.

Main Methods:

  • Retrospective cohort study of early-stage breast cancer patients (2010-2018).
  • Logistic regression analysis to identify predictors of positive SLNB.
  • Analysis of patient demographics, tumor characteristics, and SLNB results.

Main Results:

  • Of 470 patients, 27.2% had positive SLNB.
  • Predictors of positive SLNB included: number of SLNs, tumor size, tumor grade, receptor status, prominent axillary lymph nodes, and lymphovascular invasion.
  • These factors were statistically significant in predicting positive SLNB (P < 0.05).

Conclusions:

  • Histopathological and radiological characteristics can predict SLNB positivity in node-negative breast cancer.
  • Identifying predictive factors aids in optimizing axillary staging and patient management.