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Updated: Aug 25, 2025

Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability
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Published on: April 2, 2015

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A Unique and Stable Polyproline I Helix Sorted out from Conformational Equilibrium by Solvent Polarity

Matteo Pollastrini1, Luca Pasquinelli1, Marcin Górecki1,2

  • 1Dipartimento di Chimica e Chimica Industriale, Università di Pisa, Via G. Moruzzi 13, Pisa 56124, Italy.

The Journal of Organic Chemistry
|October 15, 2022
PubMed
Summary

Researchers created a stable Polyproline I helical structure using (S)-indoline-2-carboxylic acid. This rare peptide secondary structure was characterized using spectroscopy, crystallography, and computational methods.

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