A Stepwise Approach to Nonoperative and Operative Management of the Diabetic Foot Ulceration
Related Experiment Video
Updated: Aug 25, 2025

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
Katherine M Raspovic1, Matthew J Johnson1, Dane K Wukich1
1Department of Orthopaedic Surgery, UT Southwestern Medical Center, 1801 Inwood Road, Dallas, TX 75309, USA.
Abstract:
There are multiple factors that lead to the development of the diabetic foot ulceration (DFU). The ultimate goal when treating DFU is to prevent amputation. Initial therapy should include debridement, maintaining a healthy wound environment, and offloading. In the setting of infection or a nonhealing DFU, surgical intervention may be necessary. The goals of this article are to discuss the key aspects of the initial examination, standard nonoperative treatment, and the operative treatment options for patients with DFU.
Related Concept Videos
Peripheral Artery Disease IV: Nursing Management
Traditional Level Of Health Care System
The preventive healthcare service includes tests for screening. Preventive health care services include identifying and reducing disease risk...
Peripheral Artery Disease V: Postoperative Nursing Management
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Peripheral Artery Disease III: Interprofessional Care
Nephrotic Syndrome III : Nursing Management

