Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Yeast Signaling01:28

Yeast Signaling

14.7K
Yeasts are single-celled organisms, but unlike bacteria, they are eukaryotes (cells with a nucleus). Cell signaling in yeast is similar to signaling in other eukaryotic cells. A ligand, such as a protein or a small molecule released from a yeast cell, attaches to a receptor on the cell surface. The binding stimulates second-messenger kinases to activate or inactivate transcription factors that further regulate gene expression. Many of the yeast intracellular signaling cascades have similar...
14.7K
The Y Chromosome Determines Maleness02:19

The Y Chromosome Determines Maleness

6.8K
The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size....
6.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preliminary study of the effect of user intent recognition errors on volitional control of powered lower limb prostheses.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2013
Same author

Promise of a low power mobile CPU based embedded system in artificial leg control.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2013
Same author

An automatic and user-driven training method for locomotion mode recognition for artificial leg control.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2013
Same author

Graphite-supported perchloric acid (HClO4-C): an efficient and recyclable heterogeneous catalyst for the one-pot synthesis of amidoalkyl naphthols.

Molecules (Basel, Switzerland)·2013
Same author

2D correlation analysis: sequential order judging.

Analytical chemistry·2013
Same author

Cofactor engineering through heterologous expression of an NADH oxidase and its impact on metabolic flux redistribution in Klebsiella pneumoniae.

Biotechnology for biofuels·2013
Same journal

Three-dimensional finite element analysis of bracketless clear aligner expansion with different buccal bone plate thicknesses.

American journal of translational research·2026
Same journal

Expression of serum inflammatory markers in colorectal cancer and their relationship with clinical pathological characteristics.

American journal of translational research·2026
Same journal

Optimal surgical timing following neoadjuvant chemoradiotherapy in patients with rectal cancer: a systematic review and network meta-analysis.

American journal of translational research·2026
Same journal

Modular FRET sensor for site-specific detection of protein arginine methylation in living cells.

American journal of translational research·2026
Same journal

The impact of nutritional risk and sarcopenia on postoperative complications and survival outcomes in elderly patients undergoing colorectal cancer surgery: a retrospective cohort study.

American journal of translational research·2026
Same journal

Imaging and clinicopathological features of a high-risk gastric stromal tumor: a case report.

American journal of translational research·2026
See all related articles

Related Experiment Video

Updated: Aug 25, 2025

De Novo Generation of Somatic Stem Cells by YAP/TAZ
13:05

De Novo Generation of Somatic Stem Cells by YAP/TAZ

Published on: May 7, 2018

9.1K

Knowledge base and emerging trends in YAP1 research.

Rong Xu1,2, Zhiying Yang1,2,3, Jiahui Fan1,2

  • 1NHC Key Laboratory of Carcinogenesis, Cancer Research Institute and School of Basic Medicine, Central South University Changsha, Hunan, China.

American Journal of Translational Research
|October 17, 2022
PubMed
Summary
This summary is machine-generated.

Research on Yes-associated protein 1 (YAP1) shows a steady increase, with a focus on cancer therapy. Global collaboration is active, highlighting YAP1

Keywords:
CiteSpaceVOSviewerYAP1bibliometric analysiscitation burstinesshippo signaling pathway

More Related Videos

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
09:55

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

3.0K
Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
11:32

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

7.0K

Related Experiment Videos

Last Updated: Aug 25, 2025

De Novo Generation of Somatic Stem Cells by YAP/TAZ
13:05

De Novo Generation of Somatic Stem Cells by YAP/TAZ

Published on: May 7, 2018

9.1K
All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System
09:55

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

3.0K
Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
11:32

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

7.0K

Area of Science:

  • Molecular Biology
  • Genetics
  • Oncology

Background:

  • Yes-associated protein 1 (YAP1) is a key coactivator in the Hippo signaling pathway, crucial for development and growth.
  • YAP1 plays significant roles in tumorigenesis, metastasis, and therapy resistance, but its full pathophysiological mechanism remains unclear.

Purpose of the Study:

  • To analyze the current status and evolutionary trends of Yes-associated protein 1 (YAP1) research.
  • To predict future research directions in YAP1 studies through bibliometric analysis.

Main Methods:

  • Bibliometric analysis of 2,928 publications from Web of Science Core Collection (WOSCC).
  • Utilized CiteSpace and VOSviewer for co-citation network mapping, co-authorship analysis, and keyword co-occurrence analysis.
  • Evaluated publication trends, country/author/journal contributions, citation bursts, and emerging research themes.

Main Results:

  • A consistent increase in YAP1 research publications.
  • China leads in co-citation, while the Journal of Biological Chemistry is the most productive journal.
  • Emerging trends focus on cancer therapy, with active global collaboration and Bin Zhao identified as a key collaborator.

Conclusions:

  • YAP1 research is in a rapid developmental stage with significant global collaboration.
  • Future studies are likely to focus on the mechanism and clinical significance of YAP1 in cancer.