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Updated: Aug 25, 2025

A Within-Subject Experimental Design using an Object Location Task in Rats
Published on: May 6, 2021
Revisiting an Analysis of Threats to Internal Validity in Multiple Baseline Designs
Timothy A Slocum1, P Raymond Joslyn1, Beverly Nichols1
1Utah State University, 2865 Old Main Hill, Logan, UT 84322 USA.
Abstract:
In our previous article on threats to internal validity of multiple baseline design variations (Slocum et al., 2022), we argued that nonconcurrent multiple baseline designs (NCMB) are capable of rigorously demonstrating experimental control and should be considered equivalent to concurrent multiple baselines (CMB) in terms of internal validity. We were fortunate to receive five excellent commentaries on our article from experts in single-subject research design-four of whom endorsed the conclusion that NCMBs should be considered strong experimental designs capable of demonstrating experimental control. In the current article, we address the most salient points made in the five commentaries by further elaborating and clarifying the logic described in our original article. We address arguments related to classic threats including maturation, testing and session experience, and coincidental events (history). We rebut the notion that although NCMBs are strong, CMBs provide an increment of additional control and discuss the application of probability-based analysis of the likelihood of threats to internal validity. We conclude by emphasizing our agreement with many of the commentaries that selection of single-case experimental designs should be based on the myriad subtleties of research priorities and contextual factors rather than on a decontextualized hierarchy of designs.
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