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[Treatment and prevention of monkeypox]
Fernando de la Calle-Prieto1, Miriam Estébanez Muñoz2, Germán Ramírez2
1Unidad de Patología Importada y Salud Internacional, CSUR para Patología Tropical Importada Adultos y Pediatría, Unidad de Aislamiento de Alto Nivel, Hospital Universitario La Paz-Carlos III-Cantoblanco. IdiPAZ. CIBERINFEC. Madrid, España.
Enfermedades Infecciosas Y Microbiologia Clinica
|October 17, 2022
Summary
Monkeypox, a viral zoonosis, is spreading globally. This document compiles essential scientific information on its epidemiology, antiviral treatments, and smallpox vaccine efficacy for emerging regions.
Area of Science:
- Virology
- Epidemiology
- Public Health
Context:
- Monkeypox (MPX) is a zoonotic viral disease endemic to parts of Africa.
- Global incidence has increased, with sustained transmission outside endemic areas observed since May 2022.
- MPX represents a newly emerging infectious disease in many health systems, necessitating updated epidemiological understanding.
Purpose:
- To compile and synthesize current scientific information on monkeypox.
- To review the epidemiological patterns of MPX in non-endemic settings.
- To assess available antiviral treatments and prophylactic measures, including smallpox vaccine efficacy.
Summary:
- Monkeypox spreads via direct contact with infectious fluids and skin lesions.
- Antiviral treatments have shown efficacy in animal models with good clinical tolerance.
- Smallpox vaccines demonstrate a protective effect against monkeypox, warranting further investigation.
Impact:
- Provides a consolidated resource for healthcare professionals and researchers managing the emerging MPX outbreak.
- Facilitates informed decision-making regarding treatment and prevention strategies.
- Highlights the need for continued research into MPX epidemiology and control measures.
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