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Updated: Aug 25, 2025

Recording Electrical Currents across the Plasma Membrane of Mammalian Sperm Cells
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Na/K-ATPase and Regulation of Sperm Function

Jacob C Thundathil1, Gayathri D Rajamanickam2, John P Kastelic1

  • 1Department of Production Animal Health, Faculty of Veterinary Medicine, University of Calgary, Calgary, Alberta, Canada.

Animal Reproduction
|October 17, 2022
PubMed
Summary

The alpha-4 isoform of Na/K-ATPase (ATP1A4) plays a key role in sperm function and fertility. ATP1A4 levels in sperm can predict bull fertility, offering a novel biomarker for male fertility assessments.

Keywords:
Na/K-ATPasebull spermouabain.

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