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Antigens Protected Functional Red Blood Cells By The Membrane Grafting Of Compact Hyperbranched Polyglycerols
Published on: January 2, 2013
Peptide modification on the interior surface of red blood cell ghosts for construction of catalytic reactors
Honoka Matsumoto1, Kentaro Okuichi1, Hiroshi Imamura1
1Department of Applied Chemistry, College of Life Sciences, Ritsumeikan University, 1-1-1, Noji-higashi, Kusatsu, Shiga, 525-8577, Japan. koshi@fc.ritsumei.ac.jp.
Abstract:
We have succeeded in in situ synthesis of gold nanoparticles (Au NPs) on the interior surfaces of red blood cell ghosts (RBCGs) with a cytoskeleton chemically conjugated to a gold-binding peptide. The Au NP-deposited RBCG with the peptide exhibits enhanced catalytic reactivity for the reduction of 4-nitrophenol due to the uniform distribution of the Au NPs on the inner surface and the coverage of the Au NPs surface with the peptide.

