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Updated: Aug 25, 2025

Enrichment of Mammalian Tissues and Xenopus Oocytes with Cholesterol
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Cholesterol: Enhancing FGF2 translocation in unconventional secretion.

Haodong Wang1,2, Min Zhang3, Liang Ge1,2

  • 1State Key Laboratory of Membrane Biology, Tsinghua University-Peking University Joint Center for Life Sciences, Beijing, China.

The Journal of Cell Biology
|October 18, 2022
PubMed
Summary

Cholesterol promotes the secretion of fibroblast growth factor (FGF2) by enhancing its binding to PI(4,5)P2 and altering cell membrane properties for translocation.

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