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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Glaucoma: Overview01:25

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Nephrotic Syndrome II : Assessment and Medical Management01:26

Nephrotic Syndrome II : Assessment and Medical Management

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IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
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Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

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The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
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Pericarditis III: Medical Management

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The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
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Articles linked to this work by shared authors, journal, and citation graph.

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Diagnosis, treatment and monitoring of pediatric Behçet's disease: Systematic literature review informing the ISSAID/PRES recommendations.

Autoimmunity reviews·2026
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Deconstructing White Dot Syndromes-Multimodal Imaging in Uveitis (MUV) Taskforce: Report 11.

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Adalimumab-Induced Changes in NK Cells Phenotype, Receptors, and Functions After Clinical Remission of Behçet's Uveitis.

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Related Experiment Video

Updated: Aug 25, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
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Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis

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Uveitis in Behçet disease - an update.

Ilknur Tugal-Tutkun1,2

  • 1Department of Ophthalmology, Istanbul Faculty of Medicine, Istanbul University.

Current Opinion in Rheumatology
|October 18, 2022
PubMed
Summary

Behçet disease (BD) uveitis, a major cause of morbidity, is better understood with new criteria and algorithms. Advanced therapies like interferon-α, infliximab, and adalimumab show superior efficacy for managing this ocular condition.

Area of Science:

  • Ophthalmology
  • Rheumatology
  • Immunology

Background:

  • Uveitis is a significant manifestation of Behçet disease (BD), often leading to high morbidity.
  • Recent data review focuses on advancements in understanding and managing BD uveitis.

Approach:

  • Review of recently published data on Behçet disease uveitis.
  • Analysis of classification criteria, diagnostic algorithms, and treatment outcomes.

Key Points:

  • Male predominance and posterior segment inflammation are common in BD uveitis.
  • Poor visual outcomes are predicted by high uveitis severity, posterior pole leakage on fluorescein angiography, and outer retinal disruption on OCT.
  • OCT-angiography may reveal subclinical retinal capillary changes.

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Related Experiment Videos

Last Updated: Aug 25, 2025

Primed Mycobacterial Uveitis PMU as a Model for Post-Infectious Uveitis
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Published on: December 17, 2021

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Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model
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Conclusions:

  • New classification criteria and diagnostic algorithms aid in patient selection and prediction of BD uveitis.
  • Fluorescein angiography and OCT are standard imaging tools; OCT-angiography's clinical relevance is under investigation.
  • Interferon-α, infliximab, and adalimumab demonstrate superior efficacy over conventional therapies for BD uveitis.