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Updated: Aug 25, 2025

Assessing Dyslexia at Six Year of Age
Published on: May 1, 2020
Clinical Reasoning: A 6-Year-Old Girl With Right-Sided Pain and Weakness
Cristina M Gaudioso1, Rachel Zolno2, Anne Wagner2
1From the Washington University Pediatric MS, Other Demyelinating Disease Center, St. Louis, MO. gaudioso@wustl.edu.
Abstract:
We outline the case of a 6-year-old girl presenting with a 2-week course of waxing and waning neurologic symptoms, including right-sided pain, weakness, dizziness, and difficulty walking. Her examination was notable for right-sided weakness, hyperreflexia, and dysmetria. Diagnostic evaluation was significant for MRI with numerous T2 hyperintense, T1 hypointense, and T1-enhancing lesions located in the juxtacortical and periventricular regions, corpus callosum, brainstem, and spinal cord; positive CSF oligoclonal bands; negative serum aquaporin-4 immunoglobulin G (IgG) and myelin oligodendrocyte glycoprotein IgG; and positive serum Epstein-Barr viral capsid antigen IgG.
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