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Updated: Aug 25, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Systematic online academic resources (SOAR) review: Sickle cell disorders
Sara Alavian1, Prince Asare-Agbo2, Teresa M Chan3
1Royal College Emergency Medicine Training Program, Division of Emergency Medicine, Department of Medicine McMaster University Hamilton Ontario Canada.
This study systematically reviewed Free Open-Access Medical Education (FOAM) resources on sickle cell disease (SCD). Only 15.1% of reviewed FOAM content met high-quality standards, highlighting a need for improved quality assessment in medical education.
Area of Science:
- Medical Education
- Emergency Medicine
- Hematology
Background:
- Free Open-Access Medical Education (FOAM) is widely used in emergency medicine.
- FOAM resources often lack traditional peer review, necessitating quality assessment by readers.
- Assessing the quality of FOAM on sickle cell disease (SCD) is crucial for reliable medical education.
Purpose of the Study:
- To systematically assess the quality of FOAM resources related to sickle cell disease (SCD).
- To identify high-quality FOAM resources for SCD education.
- To provide guidance for trainees, educators, and FOAM authors on SCD content.
Main Methods:
- A systematic online academic resource (SOAR) review methodology was employed.
- Keywords for SCD were searched across FOAM Search and top FOAM websites.
- The revised Medical Education Translational Resources Impact and Quality (rMETRIQ) tool was used for full-text quality assessment of 53 resources.
Main Results:
- Out of 520 initially identified resources, 53 underwent quality assessment.
- Only 8 resources (15.1%) achieved a high-quality score (rMETRIQ ≥ 16).
- Common topics included acute chest syndrome, pain crisis, and general SCD review; 21% of resources scored below 7 (potentially poor quality).
Conclusions:
- A systematic approach successfully identified and appraised FOAM resources on SCD.
- A curated list of eight high-quality FOAM resources is now available.
- This list can inform recommendations for trainees and educators, and guide FOAM authors.
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08:23Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
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