Isolated Percutaneous Endoscopic Gastrostomy Site Metastasis From Hypopharyngeal Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma (HNSCC) is a relatively uncommon malignancy due to the human papillomavirus or environmental factors such as excessive alcohol or tobacco use. Its most common metastatic locations are the lungs, bone, and liver. We are reporting a much more exceedingly rare site, a percutaneous endoscopic gastrostomy (PEG) site. HNSCC metastases and recurrences are commonly seen; however, they present complex challenges to manage successfully. Our presenting patient had an initial diagnosis of hypopharyngeal squamous cell carcinoma and then developed an isolated metachronous metastatic tumor at the site of his gastrostomy tract approximately one year later.