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Published on: December 15, 2011
Rare Co-Existent Dermatitis Herpetiformis and Psoriasis in a Child: A Causal Relationship?
Ajeet Singh1, Satyaki Ganguly1, Namrata Chhabra1
1Dermatology, All India Institute of Medical Sciences, Raipur, IND.
Insights
Dermatitis herpetiformis (DH) and psoriasis, both linked to celiac disease, can co-exist. A gluten-free diet improved both conditions in a pediatric patient, suggesting a potential link beyond coincidence.
Area of Science:
- Immunodermatology
- Gastroenterology
- Genetics
Background:
- Dermatitis herpetiformis (DH) is an autoimmune blistering skin condition associated with gluten sensitivity and celiac disease (CD).
- Psoriasis is a chronic inflammatory skin disease with documented associations with celiac disease.
- The co-occurrence of DH and psoriasis is uncommon, prompting investigation into potential sharedPathways.
Abstract:
Dermatitis herpetiformis (DH) is an auto-inflammatory skin disease that is linked to gluten sensitivity and is related to celiac disease (CD). Psoriasis is an inflammatory skin disorder found to have an association with the celiac disease, according to various genetic and epidemiological studies. We report a 12-year-girl who presented with multiple tense blisters along with red raised, scaly and itchy lesions over her body. She was a known case of psoriasis and was diagnosed as dermatitis herpetiformis in an immunofluorescence study. In this case report, we want to highlight the fact that the co-existence of dermatitis herpetiformis and psoriasis could be more than a mere coincidence. In our patient's previously uncontrolled psoriasis and dermatitis herpetiformis both improved after a gluten-free diet along with systemic therapy.
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