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Updated: Aug 25, 2025

Models of Murine Vaginal Colonization by Anaerobically Grown Bacteria
Published on: May 25, 2022
[Vaginal microbiota and vaginosis]
Anna Surbone1, Basile Pache1, Patrice Mathevet1
1Service de gynécologie-obstétrique, Département femme-mère-enfant, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Abstract:
The vaginal microbiota is essentially composed of bacteria of the Lactobacillus genus. These bacteria, by their presence, prevent vaginal contamination by other potentially aggressive germs. Disturbances of the microbiota lead to a pathological state called dysbiosis, one of the most frequent pathogenic aspects of which is bacterial vaginosis. This vaginal state results in nauseating leucorrhoea induced by the proliferation of aero-anaerobic bacteria. Bacterial vaginosis is a source of different clinical impacts: increased risk of genital infection with many pathogens, loss of chance in medically assisted procreation, increased risk of premature delivery. The treatment of bacterial vaginosis must take into account the restitution of a normal microbiota.
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