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Updated: Aug 24, 2025

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology
Published on: December 15, 2017
Harnessing bioengineered microbes as a versatile platform for space nutrition
Briardo Llorente1,2, Thomas C Williams3,4, Hugh D Goold3,4,5
1ARC Center of Excellence in Synthetic Biology, Macquarie University, Sydney, NSW, 2109, Australia. briardo.llorente@mq.edu.au.
Abstract:
Human enterprises through the solar system will entail long-duration voyages and habitation creating challenges in maintaining healthy diets. We discuss consolidating multiple sensory and nutritional attributes into microorganisms to develop customizable food production systems with minimal inputs, physical footprint, and waste. We envisage that a yeast collection bioengineered for one-carbon metabolism, optimal nutrition, and diverse textures, tastes, aromas, and colors could serve as a flexible food-production platform. Beyond its potential for supporting humans in space, bioengineered microbial-based food could lead to a new paradigm for Earth's food manufacturing that provides greater self-sufficiency and removes pressure from natural ecosystems.
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