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Updated: Aug 24, 2025

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Published on: January 19, 2024
Extrafacial Melasma: A Scenario Less Explored.
Manju Daroach1, Keshavamurthy Vinay1, Anuradha Bishnoi1
1Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Extrafacial melasma often progresses from facial melasma over time, particularly in postmenopausal women. Understanding this natural course aids in diagnosis and management of this rare skin condition.
Area of Science:
- Dermatology
- Pigmentary disorders
Background:
- Extrafacial melasma is a rare condition, often seen in postmenopausal women.
- Its etiology and disease course are not well understood.
Purpose of the Study:
- To investigate the natural progression of extrafacial melasma.
- To understand the timeline and patterns of its development.
Main Methods:
- A history questionnaire was administered to patients diagnosed with extrafacial melasma.
- Data collected included onset, duration, progression, sites of involvement, and treatment history.
Main Results:
- Fifteen postmenopausal women (mean age 51.2 years) were studied.
- 93% had a history of facial melasma, with centrofacial melasma being the most common initial presentation (66%).
- Facial melasma cleared in a mean of 18.2 years, with extrafacial melasma appearing around 20 years.
Conclusions:
- Clinical patterns of melasma appear to evolve sequentially.
- Centofacial melasma frequently precedes the development of extrafacial melasma, indicating a progressive nature of the disease.
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