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Related Experiment Video

Updated: Aug 24, 2025

A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer

A Flow Cytometry-Based Cell Surface Protein Binding Assay for Assessing Selectivity and Specificity of an Anticancer Aptamer

Published on: September 13, 2022

Aptamer-Based Cancer Cell Analysis and Treatment.

Limei Wu¹, Yutong Zhang¹, Zhimin Wang¹

¹Molecular Science and Biomedicine Laboratory (MBL), State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering College of Biology, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan, 410082, P. R. China.

|October 20, 2022

Summary

Aptamers, or "chemical antibodies," offer precise cancer cell analysis and treatment. These DNA/RNA molecules provide advantages like easy synthesis and high selectivity for advanced cancer theranostics.

Keywords:

aptamers cancer theranostics cell imaging cell recognition targeted therapy

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Area of Science:

Biochemistry
Molecular Biology
Nanotechnology

Background:

Aptamers are single-stranded DNA/RNA oligonucleotides with high affinity and selectivity for targets.
Known as "chemical antibodies," aptamers offer advantages like easy synthesis, modification, programmability, and biocompatibility.

Purpose of the Study:

To review recent advancements in aptamer-based strategies for cancer theranostics.
To highlight the application of aptamers in precise cancer cell analysis and treatment.

Main Methods:

Literature review of recent studies on aptamer development and application in cancer research.
Focus on aptamer-based strategies for cancer diagnosis and therapy.

Main Results:

Aptamers demonstrate significant potential as molecular tools in cancer theranostics.
Recent progress shows aptamer-based strategies enable precise analysis and targeted treatment of cancer cells.

Conclusions:

Aptamers are highly promising for developing novel cancer diagnostic and therapeutic agents.
Further research into aptamer applications will advance cancer theranostics.