A comparative study of midazolam and thiopentone for induction of anesthesia for short operations

Midazolam has been studied as an induction agent compared to thiopentone in forty patients. Few drawbacks were noted, but these included a fall in systolic and diastolic blood pressures, respiratory upsets and longer induction and recovery times compared to thiopentone. The difference between these two agents is statistically significant. The midazolam group took a longer time (after discontinuation of inhalational anesthetics) to respond to commands and perform certain tasks during the process of recovery. We concluded that thiopentone is preferable to midazolam as an induction agent.