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Retinoic Acid-Induced Limb Duplications

Malcolm Maden1, Trey Polvadore2

  • 1Department of Biology & UF Genetics Institute, University of Florida, Gainesville, FL, USA. malcmaden@ufl.edu.

Methods in Molecular Biology (Clifton, N.J.)
|October 22, 2022
PubMed
Summary

Retinoic acid (RA) and retinoids can induce limb duplications in salamanders by respecifying limb axes. New synthetic retinoids offer precise tools for studying limb regeneration and positional information.

Keywords:
Limb DevelopmentLimb DuplicationsLimb RegenerationRAR AgonistsRARsRetinoic Acid

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