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Monkeypox virus: Future role in Human population.

Abdullah Farasani1

  • 1Medical Research Center, Jazan University, Jazan, Saudi Arabia; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Saudi Arabia.

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Summary
This summary is machine-generated.

Monkeypox virus (MPXV) is a rare, emerging zoonotic disease. While not as contagious as COVID-19, MPXV requires proper public health measures for control and future vaccine development.

Keywords:
DiagnosticsMonkey Pox (MPX)Monkey Pox Virus (MPXV)Vaccines and smallpox

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Area of Science:

  • Virology
  • Public Health
  • Epidemiology

Background:

  • Monkeypox virus (MPXV) is a rare zoonotic disease causing pustules, with origins in Africa since 1970.
  • Transmission occurs through animal-to-human contact and human-to-human via bodily fluids or respiratory droplets.
  • MPXV is an emerging global health concern with sporadic outbreaks documented.

Purpose of the Study:

  • To review diagnostic methods for Monkeypox virus.
  • To document current treatments, including vaccines, for MPXV.
  • To explore the future role of MPXV in human populations.

Main Methods:

  • Diagnosis relies on clinical presentation and laboratory tests like cell-culture, serology, and Polymerase Chain Reaction (PCR).
  • Treatment involves antivirals approved for Orthopoxvirus, such as tecovirimat.
  • Smallpox vaccines offer protection against MPXV.

Main Results:

  • MPXV diagnosis is confirmed via clinical and laboratory assessments.
  • Tecovirimat demonstrates up to 85% efficacy in treating MPXV.
  • The fatality rate is higher in children (3-10%) compared to adults.

Conclusions:

  • MPXV is less contagious than COVID-19 but necessitates strict control measures.
  • Challenges in controlling MPXV exist, highlighting the need for ongoing research.
  • Future global studies on MPXV antivirals and vaccines are recommended for eradication.