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Updated: Aug 24, 2025

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
[Basic immunization of vaccines is fundamental, and booster immunization is the guarantee: Booster immunization and
1Academy of Preventive Medicine, Shandong University/Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Jinan 250014, China.
Abstract:
Booster immunization is the following vaccination after a period of vaccine primary immunization schedule in order to maintain immunity against a certain pathogen. In this article, the immunological mechanism of booster immunization is elaborated, and the effectiveness and public health value of booster immunization for common vaccines is discussed. Subsequently, three hot issues of general concern in booster immunization are addressed, and the public health viewpoint that "Primary immunization of vaccines is fundamental, and booster immunization is the guarantee" is emphasized, so as to raise awareness of the importance and necessity of booster immunization as well as to provide scientific evidences for vaccine immunization practice.
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