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Related Concept Videos

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

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Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
393
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

349
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
349
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

294
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
294
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

172
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
172
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

192
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

525
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Investigating Intestinal Inflammation in DSS-induced Model of IBD
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Prognostication in inflammatory bowel disease.

Elizabeth A Spencer1, Manasi Agrawal2,3, Tine Jess3,4

  • 1Division of Pediatric Gastroenterology and Nutrition, Icahn School of Medicine, Mount Sinai Hospital, New York, NY, United States.

Frontiers in Medicine
|October 24, 2022
PubMed
Summary
This summary is machine-generated.

Personalized inflammatory bowel disease (IBD) care requires predicting patient outcomes. This review covers current and future predictors, emphasizing global collaboration for optimized treatment strategies.

Keywords:
Crohn's diseaseinflammatory bowel diseaseprecision medicineprognosticationulcerative colitis

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Area of Science:

  • Gastroenterology
  • Immunology
  • Personalized Medicine

Background:

  • Inflammatory bowel diseases (IBD) present significant heterogeneity in patient populations.
  • Optimizing IBD management necessitates accurate prognostication of disease course and treatment response.

Purpose of the Study:

  • To review existing and emerging predictors of outcomes in IBD.
  • To highlight the importance of global collaboration in utilizing prognostication tools for personalized IBD care.

Main Methods:

  • Comprehensive literature review of current and emerging outcome predictors in IBD.
  • Discussion of the role of collaborative efforts and clinical tools for prognostication.

Main Results:

  • Several predictors for IBD patient outcomes are currently available.
  • Future research is identifying novel biomarkers and predictive models for near and far horizons.

Conclusions:

  • Accurate prognostication is crucial for tailoring treatment strategies in IBD.
  • Worldwide collaborative initiatives are essential for the effective clinical implementation of IBD prognostication tools.