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Published on: August 19, 2020
[Jaundice in Young Children]
Insights
This review covers childhood jaundice, focusing on persistent cases that may indicate cholestasis. It highlights key differential diagnoses and introduces essential diagnostic imaging techniques for accurate evaluation.
Area of Science:
- Pediatrics
- Medical Imaging
- Neonatology
Context:
- Jaundice is a common condition in neonates, with physiological jaundice affecting over half of full-term infants.
- Persistent or late-onset jaundice in children necessitates evaluation for cholestasis.
Purpose:
- To review differential diagnoses for pediatric cholestasis.
- To introduce diagnostic imaging techniques for evaluating cholestasis in children.
Summary:
- This review covers common causes of jaundice in children, focusing on cholestasis.
- It details the role of imaging studies in differentiating conditions such as biliary atresia and other extrahepatic bile duct disorders.
- Normal imaging findings are also presented.
Impact:
- Aids clinicians in diagnosing the cause of prolonged jaundice in pediatric patients.
- Provides a guide to essential imaging modalities for evaluating biliary system disorders in children.
- Enhances understanding of cholestasis differential diagnoses and imaging interpretation.
Abstract:
Jaundice in children have various etiologies. Among them, physiological jaundice is a very common disease observed in more than half of full-term neonates. When jaundice persists or develops after 2 weeks of age, the total/direct bilirubin is measured in consideration of the possibility of cholestasis. In case of cholestasis, imaging studies differentiate biliary atresia and other disorders of the extrahepatic bile ducts. In this review, we briefly presented the major differential diseases of cholestasis in children and introduced diagnostic imaging techniques, including normal findings.
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