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What hematological and endocrinal indicators are important in COVID-19 infection?

Alireza Ostadrahimi1, Vahideh Sadra2, Amir Bahrami2

  • 1Nutrition Research Center, Department of Clinical Nutrition, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Health Promotion Perspectives
|October 24, 2022
PubMed

Insights

Hematological and endocrine markers like free triiodothyronine, calcium, vitamin D, ESR, and ferritin show significant differences between COVID-19 survivors and non-survivors, impacting prognosis. Further research is needed to fully understand these effects.

Area of Science:

  • Endocrinology
  • Hematology
  • Infectious Diseases

Background:

  • Endocrine system involvement in COVID-19 requires further investigation.
  • Understanding hematological and endocrine changes is crucial for COVID-19 patient outcomes.

Purpose of the Study:

  • To assess the relationship between hematological and endocrine parameters in COVID-19 patients.
  • To identify potential biomarkers for COVID-19 prognosis.

Main Methods:

  • A cross-sectional study included 320 confirmed COVID-19 patients (215 survivors, 105 non-survivors).
  • Serum samples were analyzed for hematological, biochemical, and hormonal parameters.

Main Results:

  • Significant differences observed in free triiodothyronine (FT3), total calcium, vitamin D, erythrocyte sedimentation rate (ESR), and serum ferritin between survivors and non-survivors.
  • FT3, calcium, vitamin D, ESR, and ferritin levels were associated with COVID-19 patient outcomes.

Conclusions:

  • Hematological and endocrine factors are important in predicting COVID-19 prognosis.
  • Further large-scale studies are necessary to elucidate the precise impact of COVID-19 on the endocrine system.

Keywords:
CoronavirusEndocrine systemFree vitamin DHematologyTriiodothyronine

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