[CME: Diagnostic Approach and Management of Thrombotic Microangiopathy]

Tabea Sutter1, Thomas Fehr1, Reto Venzin2

  • 1Klinik für Innere Medizin, Kantonsspital Graubünden, Chur, Schweiz.

Praxis
|October 26, 2022
PubMed

CME: Diagnostic Approach and Management of Thrombotic Microangiopathy Abstract. Thrombotic microangiopathies (TMA) are characterized by organ thrombosis induced by endothelial injury. They present with thrombocytopenia, hemolytic anemia and schistocytes. In case of an underlying disease-causing TMA, the treatment of the underlying disease is essential. Primary TMAs are divided into thrombotic thrombocytopenic purpura, hemolytic-uremic syndrome and atypical hemolytic-uremic syndrome. Differentiation of these entities is essential, as fast initiation of empiric treatment might be life-saving and disease-modifying treatments for the different entities do exist.

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