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The Association between Asthma and OSA in Children

Nicholas Garza1, Manisha Witmans2, Martina Salud3

  • 1Valley Children's Hospital, Madera, CA 93636, USA.

Children (Basel, Switzerland)
|October 27, 2022
PubMed

Insights

Pediatric obstructive sleep apnea (OSA) and asthma share bidirectional links, impacting symptoms and treatment. Recognizing their connection improves outcomes for children with these common respiratory conditions.

Area of Science:

  • Pediatric Pulmonology
  • Sleep Medicine
  • Allergy and Immunology

Background:

  • Obstructive sleep apnea (OSA) and asthma are common co-existing respiratory conditions in children.
  • Limited studies suggest a bidirectional relationship between pediatric asthma and OSA.
  • Overlap exists in symptoms, risk factors, pathophysiology, comorbidities, and management.

Purpose of the Study:

  • To highlight the relationship between OSA and asthma in children.
  • To explore shared risk factors, pathophysiology, and management strategies.
  • To emphasize the importance of early recognition for improved treatment outcomes.

Main Methods:

  • Review of existing pediatric literature on asthma and OSA.
  • Analysis of shared risk factors and pathophysiological mechanisms.
  • Synthesis of current management recommendations for co-existing conditions.

Main Results:

  • Evidence suggests a reciprocal association where asthma may predispose to OSA, and OSA can worsen asthma control.
  • Inflammation in upper and lower airways likely plays a role in their interconnectedness.
  • Current literature often evaluates aspects of this relationship independently.

Conclusions:

  • Early recognition of co-existing OSA and asthma in children is crucial for optimizing treatment.
  • A deeper understanding of the underlying mechanisms can refine medical management.
  • Addressing the interplay between these conditions can reduce morbidity in at-risk pediatric populations.

Keywords:
OSAasthmapediatrics

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