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Updated: Aug 23, 2025

Prospecting Microbial Strains for Bioremediation and Probiotics Development for Metaorganism Research and Preservation

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Published on: October 31, 2019

Marine Bioprospecting, Biocatalysis and Process Development.

Carlos J C Rodrigues^1,2, Carla C C R de Carvalho^1,2

¹Department of Bioengineering, iBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisbon, Portugal.

|October 27, 2022

Summary

Marine bacteria offer diverse enzymes for sustainable industrial applications. New methods for cultivation, screening, and microreactor-based bioprocess development accelerate the discovery and application of these novel biocatalysts.

Keywords:

biocatalyst bioprocess cultivation marine biotechnology metagenomics

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Area of Science:

Marine microbiology and biotechnology
Biocatalysis and enzyme discovery
Sustainable industrial processes

Background:

Marine environments harbor microbial diversity with unique enzymatic machinery evolved for survival.
Existing bacterial enzymes are used industrially, but novel biocatalysts are crucial for sustainable applications.
Metagenomics aids discovery but rapid bioprocess feasibility evaluation remains a challenge.

Purpose of the Study:

To review recent advancements in marine bacteria cultivation and enzyme screening.
To discuss the development of bioprocesses using microreactors and miniaturized systems.
To highlight strategies for accelerating the discovery and application of novel marine biocatalysts.

Main Methods:

Review of literature on marine bacteria cultivation techniques.
Analysis of high-throughput and in vitro screening platforms for enzyme discovery.
Discussion of small-scale approaches and process integration, including microreactors.

Main Results:

Metagenomic techniques enable discovery without cultivation, but rapid evaluation is key.
Cultivating uncultured marine bacteria requires new methodologies; isolated enzyme activity is easily measured.
Innovative screening platforms and miniaturized systems improve bioprocess development.

Conclusions:

Advancements in cultivation, screening, and microreactor technology are vital for harnessing marine biocatalysts.
Efficient bioprocess evaluation is essential for translating microbial discoveries into industrial applications.
Further integration of small-scale approaches will drive the development of commercially valuable bioprocesses.